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Here is an interesting WIRED article, which states that “science itself—through its systems of publication, funding, and advancement—had become biased toward generating a certain kind of finding: novel, attention grabbing, but ultimately unreliable. The incentives to produce positive results were so great […] that some scientists were simply locking their inconvenient data away.”
The article is about Brian Arthur Nosek, the co-founder and director of the Center for Open Science. The Center for Open Science supports researchers to plan reproducibility projects.